Muaj ntau hom plasticizers, suav nrog phthalates, aliphatic dibasic acid esters, fatty acid esters, benzene polyesters, polyol esters, epoxy hydrocarbons, alkyl sulfonates, thiab lwm yam. lub npe sib sau ua ke ntawm txog 30 hom esters tsim los ntawm phthalic acid. Tam sim no, nws yog lub cev tseem ceeb ntawm plasticizers.
PAEs tuaj yeem nkag mus rau tib neeg lub cev los ntawm kev ua pa, plab hnyuv thiab tawv nqaij. Tam sim no, kev tshawb fawb hauv tsev thiab txawv teb chaws tau pom tias cov pa phem ntawm PAEs hauv cov pej xeem yog qhov hnyav heev. PAEs tau kuaj pom nyob rau hauv cov ntshav ntawm cov menyuam ntxhais uas tsis nco qab, kuaj zis ntawm cov poj niam hnub nyoog muaj menyuam, thiab cov kua mis.
The acute toxicity of PAEs is relatively low. The LD50 of rats is 30-34 g/kg orally, 15-30 g/kg intraperitoneally, and 1-2 g/kg intravenously. The LD50 of mice is 33.32 g/kg and that of rabbits is 33.9 g/kg. , 26.3g/kg in guinea pigs. PAEs can act on the chromosomes of cells to change the number or structure of chromosomes, thereby making some tissues and cells grow out of control, resulting in tumors. PAEs have obvious anti-androgenic effects in vivo, in vitro experiments and animal models, and have an impact on the development of the endocrine and reproductive systems of infants and young children. The estrogenic effects of PAEs may be related to abnormal reproductive system development, reproductive dysfunction, reproductive system and endocrine system tumors, and nervous system development and functional damage. There have been reports of acute poisoning due to misuse of PAEs, which can cause gastrointestinal irritation, central nervous system depression, paralysis, and lower blood pressure. Chronic toxicity of PAEs is mainly manifested by decreased renal function, increased number of focal renal cysts, and renal tubular pigmentation. In addition, PAEs can also produce liver toxicity, lung toxicity, and cardiotoxicity. Long-term exposure to PAEs can cause symptoms such as polyneuritis, hypoesthesia, and numbness. Some scholars believe that the increase in asthma may also be related to people's exposure to PAEs in their daily lives.
Raws li txoj kev ua neej niaj hnub no, nws yuav luag tsis tuaj yeem zam cov plasticizers kiag li, tab sis tsis tas yuav muaj kev ntxhov siab ntau dhau, vim tias cov plasticizers raug rau hauv lub neej ib txwm yuav tsis ua mob rau tib neeg lub cev. Txawm li cas los xij, tib neeg yuav tsum hu rau cov khoom siv yas uas muaj cov yas yas kom tsawg li sai tau.
Qhov yooj yim tshaj plaws kev sib cuag nrog cov zaub mov hauv lub neej niaj hnub yog cov ntaub qhwv yas, uas tau muab faib ua polyethylene (PE) yas qhwv thiab polyvinyl chloride (PVC) yas qhwv. Yog tias cov khoom yas raug cim nrog PVC, nws txhais tau hais tias nws muaj cov yas yas. Tshwj xeeb, cov khoom noj nrog cov hnab yas yuav tsum tsis txhob muab tso rau hauv lub qhov cub microwave, tshwj xeeb tshaj yog cov nqaij, vim tias cov yas yuav tso cov tshuaj lom thaum lawv nkag rau hauv cov roj.